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現在までにWHO-IUISによって正式に登録されているラテックスアレルゲン群を、予想される生理的な役割と共にまとめると、下の表のようになります。
表. 正式に登録されているラテックスアレルゲン
正式名 | 慣用名 | 予想される生理的な役割 | 登録番号(蛋白質) | 参考文献 |
Hev b 1 | ラバーエロンゲーションファクター | ゴムラテックスの生合成に関与 | P15252 | 1 |
Hev b 2 | ベータ-1,3-グルカナーゼ | 生体防御蛋白質 | Q7XJ83, P52407 | 2 |
Hev b 3 | スモールラバーパーティクルプロテイン | ゴムラテックスの生合成に関与 | O82803 | 3 |
Hev b 4 | マイクロヘリックスコンポーネント | 生体防御蛋白質 | Q8WPJ2 | 4 |
Hev b 5 | 酸性ラテックス蛋白質 | − | Q39967 | 5 |
Hev b 6.01 Hev b 6.02 Hev b 6.03 |
プロヘベイン, ヘベインプレプロテイン ヘベイン プロヘベインC-末端側蛋白質 |
生体防御蛋白質 (ゴムラテックスの凝集に関与) |
O49860, P02877, P80359 | 6 |
Hev b 7.01 = Hev b 13 (renamed) Hev b 7.02 |
パタチン類似蛋白質(B-serum) パタチン類似蛋白質(C-serum) |
生体防御蛋白質 天然ゴム生合成の阻害 |
O04008, O81984, O65811, Q9SEM0 |
7 |
Hev b 8 | ラテックス プロフィリン | 構造蛋白質 | O65812, Q9STB6, Q9M7N0, Q9M7M9, Q9M7M8, Q9LEI8 |
8 |
Hev b 9 | ラテックス エノラーゼ | 糖分解酵素 | Q9LEJ0, Q9LEI9 | 9 |
Hev b 10 | Mn-スーパーオキサイド ジスムターゼ | ラジカルの消去 | P35017, Q9STB5, Q9FSJ2 | 10 |
Hev b 11 | クラスTエンドキチナーゼ | 生体防御蛋白質 | Q949H3, Q8GUD7 | 11 |
Hev b 12 | 脂質輸送タンパク質 | 生体防御蛋白質 | Q8RYA8 | 12 |
Hev b 13 (= Hev b 7.01) | ラテックス エステラーゼ | 生体防御蛋白質 | Q7Y1X1 | 13 |
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